The preparation of alginate beads requires an understanding of chemistry and the proper use of the tools involved in the preparation. Alginate beads can be made with a mixture of sodium, calcium or genetically engineered cells. It is vitally important to exercise precision in measurement and procedure and to follow the time requirements for mixing and drying to ensure proper formation.
Fill a beaker three quarters full of the calcium chloride solution.
Fill a syringe that has an 18G needle with the solution of sodium alginate.
Slowly squeeze the solution of sodium alginate from the syringe into the calcium chloride solution in small drops until the syringe is empty.
Gently shake the beaker to ensure the beads do not stick together. Remove the beads from the calcium chloride solution after five minutes and allow to air dry.
Wash the surface of the beads with water after they have dried to remove any excess calcium chloride.