Xylene substitutes

Written by l.w. westerfield | 13/05/2017
Xylene substitutes
The high toxicity of xylene has inspired the production of numerous substitutes. (Toxic hazard flag image by Stasys Eidiejus from Fotolia.com)

Xylene, also referred to as xylol, is any of three different isomeric liquid substances used as a solvent in the manufacture of dyes, resins, insecticides, fuels, perfumes and films. Xylene is highly toxic and can cause a host of dangerous side effects, including damaged neurological function, fatigue, mood swings, irritability and dizziness. Scientists have thus sought and developed a number of safer xylene substitutes, including the following list of leading industry alternatives.

Pro-Par Clearant

Developed by Anatech Ltd., Pro-Par Clearant is an ideal alternative to xylene. The formula possesses the same evaporation rate, penetration rate and drying time as xylene, is recyclable and sustains a small degree of water tolerance.


An almost odourless formula with low toxicity levels, Clear-Advantage is another xylene substitute available from Polysciences, Inc. (see Resources). Clear-Advantage is distinctive in that it offers faster drying time than xylene.

Clear-Rite 3

Clear-Rite 3, produced by Richard-Allan, is similar to Pro-Par Clearant in that it has the same evaporation rate, penetration rate and drying time of xylene. Unlike Pro-Par, however, Clear-Rite has zero water tolerance.


Histosolve is a Shandon product and another xylene mimic with equal evaporation rate, penetration time and drying time. It is also recyclable, but like Clear-Rite it has zero water tolerance.

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