How to recognize side-effects from prednisone

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Prednisone is a type of medication that is termed a steroid. It is an anti-inflammatory, meaning that it prevents the body from producing substances that cause inflammation. There are possible side effects with Prednisone use.

Skill level:


  1. 1

    Watch for weight gain and increased appetite. These are common, and usually harmless, side effects. Hand-in-hand with weight gain is restlessness and potential indigestion.

  2. 2

    Note any sweating and flushing of the face, a feeling of warmth or a sensation of a hot flush. These side effects may cause problems, but are not particularly dangerous.

  3. 3

    Be on guard for severe mood swings and severe depression. If they begin, call the doctor, but never stop Prednisone on your own.

  4. 4

    Watch for an allergic, or anaphylactic, reaction. Be aware of shortness of breath, swelling of the mouth, swelling of the lips or hives. If they start, immediately call an ambulance. An anaphylactic reaction can be fatal.

Tips and warnings

  • Avoid being around sick people. The least little illness can make you ill because your immune system has been compromised.
  • Read the instructions that come with the Prednisone prescription and keep them accessible. Advise someone who either lives with you or sees you regularly that you are on a new medication. Have another person watching you.
  • Never discontinue Prednisone on your own.

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