What can cause a liver lesion?

Updated July 19, 2017

A number of factors can cause a liver lesion, including liver disease caused by genetic factors, poor diet, excessive alcohol consumption and viral diseases. Internal injuries can also cause liver lesions.

Fatty Liver Disease

Fatty liver disease is the accumulation of fat in the liver which can cause lesions and scarring. Although it is normal to have some fat present in the liver, if it reaches in excess of 10 per cent of your liver's weight you will be diagnosed with fatty liver disease.


With cirrhosis, the liver deteriorates due to chronic injury. The liver is so damaged that scar tissue replaces healthy liver tissue, ultimately impairing liver function.

Internal Injuries

Liver lesions can be caused by trauma to the abdominal region due to motor vehicle accidents or stabbing wounds. This type of liver lesion occurs more frequently in males.


Hemochromatosis is a condition where liver tissue is damaged by an excessive accumulation of iron in the body. This is a genetic condition that is caused by the body absorbing excessive levels of dietary iron.

Hepatitis B and C

Liver lesions can also be caused by the viral infections hepatitis B and C, which cause inflammation and infection of the liver and can become chronic. These conditions can be so severe they can cause cirrhosis and liver cancer.

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Maria Tarallo is a writer from Montevideo, Uruguay. Tarallo has been writing professionally since 2000. Although her background is in journalism, over the years, she became increasingly involved in Internet marketing. It was within this environment that she further developed her concise writing style. Tarallo attended Broward Community College, and her articles are featured on websites such as Expert and Native