Side effects of effergin

Updated February 21, 2017

Effergin is a dietary supplement drink mix advertised as preventing heart disease, reducing blood pressure and improving erectile dysfunction. The primary ingredient in Effergin is the amino acid arginine, which poses a risk for side effects in some people.

Side Effects

Possible arginine side effects include abdominal pain, bloating, diarrhoea and gout, reports RxList. It may also cause headaches, an increased incidence of cold sores, numbness and swelling in your legs.

Drug Interactions

Arginine can potentially cause dangerous drops in blood pressure when taken with hypertension drugs, reports RxList. Arginine combined with the erectile dysfunction drug sildenafil or heart medications such as isosorbide or nitroglycerine may cause dizziness.


Arginine can cause changes in your blood chemistry, such as high potassium, high chloride, low sodium, low phosphate and high creatinine levels, reports the Mayo Clinic. Arginine may also cause low blood pressure, with the potential for fainting or depriving your brain or heart of oxygen.


Some patients develop severe, potentially life-threatening, allergic reactions to arginine. If you experience hives, chest pain, shortness of breath or swelling of your face or throat, seek emergency medical attention, suggests the Physicians' Desktop Reference.


Because arginine's effects upon fetal development are unknown, avoid using Effergin if you are pregnant or nursing. If you have a history of allergies, asthma, cirrhosis, hypotension, heart attack, genital herpes, diabetes or kidney or liver disease, products containing arginine may be unsafe.

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About the Author

Faith Davies has been writing professionally since 1996, contributing to various websites. She holds an LAH insurance license in the state of Pennsylvania and has experience as a bank branch manager and lending officer. Davies graduated cum laude from the University of Pittsburgh with a Bachelor of Arts in art history.