Meclizine hydrochloride is an antihistamine available in prescription and over-the-counter forms. Brands include Antivert and Dramamine, and people can buy it generically as well. It is used to treat and prevent dizziness and nausea associated with motion sickness. Numerous side effects are possible.
More Common Side Effects
Meclizine HCl, like other antihistamines, can cause blurred vision, drowsiness, dry mouth, fatigue, headaches, nervousness, sore throat and thickening of bronchial mucus.
Gastrointestinal Side Effects
Possible gastrointestinal side effects include abdominal pain, diarrhoea, increased appetite, weight gain, and worsening of gastro-oseophageal reflux disease and stomach ulcers.
Rare Side Effects
Serious side effects are rare, and more common in young children and elderly people. They include heart palpitations, irregular heartbeat, rapid heartbeat, confusion, difficulty urinating, seizures and worsening of glaucoma.
Rarely, some people can have an allergic reaction to meclizine HCl. Signs are rash or hives, itching, swelling of the throat or mouth, wheezing and difficulty breathing.
Meclizine HCl may interact with alcohol, certain high blood pressure medications, anticholinergic drugs, antipsychotic medications, anti-anxiety medications, antidepressants, muscle relaxants, narcotic pain relievers and sleep medications.