Microgynon 50 Side Effects

Updated April 17, 2017

Microgynon 50, or Alesse in the United States, is a monophasic birth control pill method. Monophasic birth control pills provide three full weeks (21 days) of active hormones, and one placebo/sugar pill week, for a woman to menstruate. This creates lighter and shorter periods as well as decreased menstrual symptoms. Beginning to use a birth control pill may result in spotting or breakthrough bleeding. Additional side effects may arise during the onset use of Microgynon 50.


While a traditional birth control prevention method, Microgynon 20 also is helpful in treating several different health conditions affecting women. Some of these conditions include painful periods (dysmenorrhoea), heavy periods (menorrhagia) and endometriosis, a painful women's health condition causing irregular menstrual periods and pain. Other hormonal and menstrual irregularities can be treated with the use of Microgynon 50, such as severe PMS.

How the Pill Works

Microgynon 50, like other birth control pills, overrides a women's natural menstrual cycle, making the body think it already has menstruated. This is achieved by preventing eggs from ripening and being released. Also, birth control pills thicken the cervical and uterine lining, making it hard for sperm to penetrate to the uterus. The use of a birth control pill also creates a more comfortable menstrual period experience for women, making it lighter and shorter. Microgynon 50 is taken orally once a day, at the same time each day.

Side Effects of Microgynon 50

Side effects include weight changes, water retention, dizziness, high blood pressure, spotting, breakthrough bleeding, nausea and/or vomiting, depression, fainting, tender breasts, lowered libido, increased risk of blood clots and liver problems. It's important to note that these side effects are not uncommon. However, if the side effects persist, consult your doctor to discuss whether or not Microgynon 50 is the right birth control pill for you.

Warnings & Microgynon 50

Microgynon 50 should not be used by women over 35 or by those who have diabetes, smoke or have a family history of high blood pressure, breast cancer or heart disease. Women who have existing kidney or gallstone problems or Crohn's disease are also discouraged from using Microgynon 50. Microgynon 50 is not safe for breastfeeding mothers, as the hormones can be passed to an infant through breast milk.

Additional Precautions

The use of Microgynon 50 can cause menstrual irregularities until the body is used to the pill. These irregularities include missed periods, spotting and breakthrough bleeding. If any additional severe symptoms occur, such as painful breathing, chest pain, jaundice or numbness on one side of the body, stop taking Microgynon 50 and consult medical help immediately.

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About the Author

Jessica Anne Elizabeth, co-founder of, is an established freelance writer and editor with a expertise in the beauty industry. Her areas of interest include hair, make-up and skincare, as well as reproductive health and pregnancy. She holds a bachelor's degree in journalism from Rutgers University.