Side effects of baytril antibiotics for dogs

Written by g.d. palmer
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Side effects of baytril antibiotics for dogs
Young puppies may develop joint problems from Baytril treatment. (puppy chews bone image by Susan Rae Tannenbaum from

Enrofloxacin, more commonly known by the brand name Baytril, is a broad-spectrum antibiotic that kills bacteria. According to, Baytril is believed to kill bacteria by keeping it from successfully synthesising DNA. This drug can only be obtained by prescription, and is effective against a variety of skin, respiratory, wound and urinary infections. However, it does have some side effects. Knowing what to expect from Baytril treatment can help dog owners act quickly when something is wrong.

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Dogs receiving Baytril treatment may suffer from nausea, vomiting, diarrhoea or loose stools and other digestive side effects associated with antibiotics. Baytril may kill beneficial bacteria in the intestines, resulting in improper digestion of food. According to the manufacturer, Baytil is less likely to cause gastrointestinal problems than many other antibiotics, since it has minimal effect on anaerobic bacteria.


Young dogs treated with Baytril may develop lesions on their joint cartilage, causing lameness or swollen joints. The manufacturer states that dogs between one and four weeks of ages can be treated with 5 to 25 mg/kg of body weight for up to ten days without suffering this problem. Longer treatment or higher dosage could cause serious, lasting joint problems. Older dogs develop some lesions, depending on treatment duration and intensity, but are unlikely to have the same problems as puppies. Most veterinarians avoid using Baytril in younger animals. Pregnant and nursing dogs may receive treatment without danger to their puppies, according to the manufacturer.

Nervous System

Very rarely, dogs treated with Baytril may show signs of central nervous system effects, including seizures and behaviour changes. Human patients undergoing therapy with similar types of drugs also sometimes suffer from insomnia, headache, and dizziness. Some dogs may develop symptoms of depression or anxiety. Vets recommend against using Baytril in dogs with epilepsy or a risk of seizures.

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