According to the University of Michigan Health System, many conditions can affect the nerves of the foot and ankle, causing numbness and other symptoms.
A growth around the nerves, called a Morton's neuroma, can cause pain, burning, tingling or numbness between your toes, especially between the third and fourth toes, and in the ball of your foot.
A pinched nerve in your back (such as one caused by a herniated disc) or buttocks can cause pain down the leg and into the foot. A pinched nerve in your ankle (tarsal tunnel syndrome) can also cause numbness.
People with poor circulation, especially those with diabetes or peripheral arterial disease, often have burning, numbness or lack of feeling in their feet.
Neurological disorders such as Parkinson's disease or cerebral palsy can cause ankle and foot numbness.
Other possible causes of numbness in the ankle and foot are leg and foot deformities, spinal problems and shoe laces tied too tight.
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