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Diosmin and hesperidin pregnancy safety

Diosmin and hesperidin are bioflavonoids (found especially in citrus fruits) that act as antioxidants to heal, strengthen and treat capillary disorders. Pregnant women suffering from haemorrhoids may find relief by taking oral tablets of diosmin and hesperidin.

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Diosmin is derived from hesperidin, which is a flavonoid extracted from a type of small orange, according to iHealthTube. It exhibits anti-inflammatory and vasoconstrictive properties that can help to reduce internal haemorrhoids and prevent future haemorrhoid flare-ups.


Haemorrhoids are swollen varicose veins in the rectal area that may itch, swell or rupture and bleed. During pregnancy, the pressure of the growing uterus on the veins in the lower body, in addition to straining that may occur during bowel movements, can lead to haemorrhoids, according to the March of Dimes.


In addition to the treatment of internal haemorrhoids, diosmin and hesperidin may be used to treat varicose veins and other peripheral vascular problems, such as poor circulation and lymphedema, according to iHealthTube.


According to a study published in the "International Journal of Gynecology and Obstetrics," short-term treatment of haemorrhoids during pregnancy with diosmin and hesperidin is considered safe, acceptable and effective. During the study, treatment did not affect pregnancy, fetal development, birth weight, infant growth or feeding.

Side Effects

Potential side effects associated with diosmin and hesperidin include headache, stomach pain, nausea and diarrhoea. Serious side affects may include chest pain, difficulty breathing, skin rash, itching, swelling of the hands or face, or tingling in the mouth.

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About the Author

A mother of three and graduate of the University of Texas, Mary Evett is the online pregnancy expert who contributes to AXS.com and CBS Local. Her passion for DIY projects is showcased monthly on the craft blog, My Crafty Spot. She is the author of the blog, Just Mom Matters.

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