Creatinine and blood urea nitrogen (BUN) are two waste products filtered by the kidneys, which takes place through a system of nephrons. Contained in each nephron is a glomerulus (filtering structure). This system maintains correct blood protein and cell levels while unneeded fluid and waste are excreted in the urine. As a dog ages and the glomeruli are damaged, creatinine levels build in the blood. A BUN:Creatine test will indicate the toxic blood level of the dog. By reducing the amount of waste the kidney must filter, the remaining functioning glomeruli can filter and reduce blood levels of creatinine.
- Skill level:
Other People Are Reading
Administer large quantities of fluids intravenously to flush and restart the kidneys. This therapy is referred to as diuresis. Diuresis helps to stimulate normal kidney cell function again. This fluid therapy should also include replacing potassium as well as other electrolytes. At home, provide fresh clean water at all times. Kidney failure causes the dog to drink in excess to help flush the kidneys. Fluid therapy helps restore metabolic balance by flushing the dog's body of creatine and nitrogenous waste .
Minimise stress on the kidney. Avoid foods high in phosphorus, which is normally filtered through the kidneys. When filtration is impaired, phosphorus levels rise in the bloodstream and calcium may be extracted from bone to restore the balance. Or if necessary, specific phosphorus binding drugs, such as Maalox, may be prescribed to lower blood levels.
Feed a high quality protein or raw meat based diet. Higher quality protein is more digestible which leads to less protein (nitrogen) waste and is therefore less taxing on the kidneys. In addition, meat based diets contain more water to assist in flushing waste, such as creatinine from the kidneys.
Reduce blood pressure with the use of angiotensin converting enzyme(ACE) inhibitors. Elevated blood pressure causes destruction of the glomeruli. ACE works by increasing the diameter of the blood vessels to decrease blood pressure and minimising the destruction of remaining functioning glomeruli. Limit salt consumption as well.
Supplement with an anti-inflammatory like omega 3 fatty acids from sources. such as fish oil which slow kidney destruction. The anti-inflammatory properties of omega 3 fatty acids reduce inflammation in the kidney. Vitamin E can be added as it acts synergistically with omega 3. By reducing inflammation in the kidney and allowing the filtration system to work, creatinine levels in the blood can be greatly reduced.
- 20 of the funniest online reviews ever
- 14 Biggest lies people tell in online dating sites
- Hilarious things Google thinks you're trying to search for