Pseudomonas UTI treatment

Updated June 13, 2017

Pseudomonas aeruginosa is an aggressive bacterium that can cause infections in many body systems. According to Emedicine, most urinary tract infections (UTIs) from Pseudomonas begin in the hospital after the bacteria are introduced into your sterile bladder by a urinary catheter, surgical procedure or medical instrument.


Antibiotics for Pseudomonas UTI may be given intravenously (IV) or orally.


Pseudomonas UTIs are typically treated with monotherapy, or a single antibiotic. If the organism spreads to your bloodstream (bacteraemia) or involves your kidneys, you may need multi-drug therapy.


IV aminoglycoside drugs such as tobramycin and gentamycin are effective forms of monotherapy for Pseudomonas UTI. Multi-drug therapy may involve aminoglycosides plus another antibiotic such as penicillin, cephalosporins like cefoxitin, or carbepenems including imipenem. Ciprofloxacin is the preferred oral drug for this infection.

Time Frame

If your UTI is confined to your bladder, you'll need 3 to 5 days of antibiotics. Complicated infections, especially in people with indwelling urinary catheters, can take 7 to 10 days to clear up. If your kidney is involved, you may need 2 to 3 weeks of antibiotics.


Your doctor will order a urine culture to determine the type of organism, and a drug sensitivity test to identify appropriate antibiotics to treat your UTI.

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About the Author

Sandy Keefe, M.S.N., R.N., has been a freelance writer for over five years. Her articles have appeared in numerous health-related magazines, including "Advance for Nurses" and "Advance for Long-Term Care Management." She has written short stories in anthologies such as "A Cup of Comfort for Parents of Children with Special Needs."