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Why Can't You Eat Grapefruit When You Are Taking a Cholestrol Lowering Statin?

Updated February 21, 2019

People who take statin medications to help lower their blood cholesterol may be advised by their doctors to avoid eating grapefruit or drinking grapefruit juice. Check with your doctor to see if the type of statin you are taking is affected by grapefruit.

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Substances found in grapefruit juice can prevent the body from breaking down certain types of statins in the liver, so they build up to high levels in the blood and can, in effect, cause an overdose.


At least one study, published in the journal Clinical Pharmacology and Therapeutics, found that only some types of statin medications are affected by consumption of grapefruit and only in certain amounts. Your doctor can tell you if you can eat grapefruit while taking a particular statin drug.

Time Frame

Grapefruit juice consumed at the same time as some statin medications can interfere with the breakdown of the medication for at least three days.


Grapefruit may not affect statin mediations if the two are consumed at different times of the day, according to Mayo Clinic cardiologist, Dr. Gerald Gau, M.D.


Red yeast rice is an alternative cholesterol-lowering medication which acts like a statin in the body. You should avoid eating grapefruit or grapefruit juice if you take red yeast rice supplements, according to University of Maryland Medical Center.

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About the Author

Molly McAdams

Molly McAdams is a writer who lives in New York City. She has covered health and lifestyle for various print and online publishers since 1989. She holds a Master of Science degree in nutrition.

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