The best ways to kill a mouse vary with personal preference. The important point is to pick the method of your choice and kill the mouse as quickly as possible. House mice carry diseases such as food poisoning and cause more damage than rats. Their droppings and urine contaminate food, clothing, furniture, books and other items.
Snap-type traps are usually preferred when there are only a few mice. These traps are easy to use and are available at grocery and hardware stores. Although cheese is promoted as the bait for these traps, mice often remove it without tripping the snap. Peanut butter is harder to remove from the tripping mechanism and almost always catches a mouse.
The upper surfaces of glue boards are coated with glue. When mice run across the board, they become stuck in the glue and die of suffocation.
Rodenticides are poisoned baits that kill rodents. Most baits are made with seed or grain that attracts mice to feed. Active ingredients in baits are usually anticoagulants such as brodifacoum, chlorophacinone, diphacinone or warfarin. After feeding on the bait, mice die from internal bleeding.
A cat that is a good mouser will kill mice. It is impossible, however, to evaluate a cat's mouse-catching abilities at the time possession is taken. Often, a cat is acquired and the owner learns that the cat is not interested in chasing mice.