It is important to plug rat holes in a way that will prevent the rats from chewing through the hole again. To do so, you'll need to make use of materials that rats cannot chew through. Most importantly, you should make every effort to prevent rats from wanting to get into your home. Make sure to keep dustbins sealed, floors clean, and food stored in containers that are not accessible to the rats.
Spot rat holes in your floor and walls. Be sure to check other out of sight areas, like inside closets, behind stoves and behind refrigerators.
Fill each interior rat hole with wire mesh.
Spread spackle over each interior hole and allow it to dry. This will seal off the hole and the wire mesh will prevent the rat from chewing back through the hole.
Mix cement with broken glass to patch holes on the exterior of your house.