Tylex is a prescription pain reliever available in the United Kingdom. Containing paracetamol and codeine phosphate, the combination is commonly called co-codamol. Paracetamol is known as acetaminophen in the United States, and the combination of acetaminophen and codeine is available there as Tylenol with codeine. Many side effects are possible.
Common Side Effects
Common side effects associated with Tylex include confusion, constipation, difficulty urinating, dizziness, dry mouth, lightheadedness, mood changes, nausea, shortness of breath, slow heart rate and vomiting.
Drugs Worsening Drowsiness
The risk of drowsiness and sedation is significant, and is worsened by taking Tylex along with certain other drugs. These include alcohol, antihistamines, antipsychotic medications, barbiturates, benzodiazepines, sleep aids, tricyclic antidepressants and other opioid painkillers.
Tolerance and Dependency
If the patient takes this medication for lengthy time frames, Tylex can cause tolerance and be less effective at relieving pain. Patients also can become dependent when taking Tylex for a long time, which can result in withdrawal symptoms when discontinuing the medicine.
Liver and Kidney Issues
Infrequently, Tylex is associated with liver and kidney damage, particularly if the patient exceeds the prescribed dosage. Alcohol intake increases the risk of liver damage.
Rare Side Effects
Rarely, rashes, blood disorders and pancreas inflammation, or pancreatitis, have occurred after prolonged use of Tylex.