Azodyl side effects

Updated December 15, 2016

Azodyl is a veterinary, over-the-counter supplement used in the treatment of kidney disease in cats and dogs. If your pet's kidney’s are failing, you are likely ready to try just about anything. However, you should understand any potential side effects of any medication before putting your pet on it.


Azodyl is made by Vetoquinol to treat azotemia or the accumulation of urea in the blood. This is usually excreted by the body in the form or urine, but in animals with renal failure, the urea builds up in the blood, effectively poisoning your pet. Azodyl’s formula uses naturally occurring, beneficial bacteria to metabolise toxins from your pet’s body, according to the Vet Info website.This slows down the rate at which toxic build-up occurs.

Side Effects

While the manufacturer or Azodyl claims that there are no reported side effects from using the product, some people have reported that the product caused vomiting and diarrhoea in pets, according to the Vet Info website.


Animals with kidney insufficiency are typically on a variety of other medications, so it’s difficult to tell whether Azodyl or something else might have caused these side effects. However, it makes sense that if Azodyl is changing the balance of beneficial bacteria in the gut and bowels, stomach upset might result at first.


If you start giving your pet Azodyl and notice undesirable side effects, you can simply lower the dosage to one that is better tolerated. Giving your pet access to plenty of fresh water immediately after giving him a capsule of Azodyl may also keep the capsule from sticking to its throat, reducing the chances that your pet will throw up.


Azodyl may be a good supplement for a pet in renal failure, as it can be used safely in conjunction with other, conventional treatments for the condition. However, if your pet experiences negative side effects, it might be best to discontinue the medication. Remember that renal failure is a terminal condition, so it will progress to death regardless of treatment. Thus, it’s important to focus on making the time a pet has left as comfortable and side effect free as possible. Also, because Azodyl is available over the counter, it's not necessary to get your veterinarian's approval before using it; however, you should discuss the product and its use with your pet's veterinarian before starting use of Azodyl. That way, your vet will have a clearer picture of all factors affecting your pet's condition for the better or worse.

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About the Author

Cynthia Gomez has been writing and editing professionally for more than a decade. She is currently an editor at a major publishing company, where she works on various trade journals. Gomez also spent many years working as a newspaper reporter. She holds a bachelor's degree in journalism from Northeastern University.